Publications

Publications

Functional genomics in stem cell models: considerations and applications

Kaivalya Shevade, Sailaja Peddada, Karl Mader, and Laralynne Przybyla published in frontiers in Cell and Developmental Biology

LGR-Funded

Compact CRISPR genetic screens enabled by improved guide RNA library cloning

Seok-Jin Heo, Lauren D. Enriquez, Scot Federman, Amy Y. Chang, Rachel Mace, Kaivalya Shevade, Phuong Nguyen, Adam J. Litterman, Shawn Shafer, Laralynne Przybyla, Eric D. Chow

LGR-Funded

A New Era in Functional Genomics Screens

Przybyla L and Gilbert L. Nature Reviews Genetics.

LGR-Collaborator

Covid Publications & Citations

Given the urgent challenge of the COVID-19 pandemic, the research award was focused on programs which were spearheading COVID-19 research through wet-lab and computational approaches with a focus on, but not limited to, CRISPR-driven approaches.

Bi-paratopic and multivalent VH domains block ACE2 binding and neutralize SARS-CoV-2

Bracken C, Lim S, Solomon P, Rettko N, Nguyen D, Zha B, Schaefer K, Byrnes J, Zhou J, Lui I, Liu J, Pance K, QCRG Structural Biology Consortium, Zhou X, Leung K, Wells J. Nature Chemical Biology

LGR-Funded

Transmission, infectivity, and neutralization of a spike L452R SARS-CoV-2 variant

Deng X, Garcia-Knight M, Khalid M, Ott M, Andino R, Chiu C et al. Cell.

LGR-Funded

The Global Phosphorylation Landscape of SARS-CoV-2 Infection

Bouhaddou M, Memon D, Meyer B, Swaney D, Beltrao P, Krogan N et al. Cell.

LGR-Funded

Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms

Gordon D, Hiatt J, Bouhaddou M, Rezelj V, Ulferts S, Braberg H, Jureka A, Obernier K,Guo J, Krogan N et al. Science.

LGR-Funded

Projects

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Findings from the lab—dive into the learnings that took place at the LGR

Publications

Covid Publications & Citations

Check out our past and present projects.